Article
Development of a single multiplex amplification refractory mutation system PCR for the detection of rifampin-resistant Mycobacterium tuberculosis.
Gene - 1 Nov 2013
Shi Xiaodan, Zhang Chen, Shi Ming, Yang Mengjie, Zhang Yi, Wang Ji, Shen Hongwei, Zhao Gang, Ma Xuejun
Abstract excerpt
A rapid and simple method for the detection of drug-resistant Mycobacterium tuberculosis is critical for the efficient treatment and control of this pathogen in developing country. Here we developed a single multiplex amplification refractory mutation system (M-ARMS) PCR, in which chimeric-primer and temperature switch PCR (TSP) strategy were included. Using this method, we detected rifampin resistance-associated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.