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Genetic testing women with newly diagnosed breast cancer: What criteria are the most predictive of a positive test?

Cancer medicine - 1 Mar 2023

Metcalfe Kelly A, Narod Steven A, Eisen Andrea, Poll Aletta, Zamani Neda, McCready David, Cil Tulin D, Wright Frances C, Lerner-Ellis Jordan, McCuaig Jeanna, Graham Tracy, Sun Ping, Akbari Mohammad R

Abstract excerpt

BACKGROUND: Knowledge of pathogenic variants in cancer-predisposing genes is important when making breast cancer treatment decisions, but genetic testing is not universal and criteria must be met to qualify for genetic testing. The objective of this study was to evaluate the pathogenic variant yield for nine cancer predisposition genes by testing criteria, singly and in combination. METHODS: Women diagnosed with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36544278
DOI: 10.1002/cam4.5515
PMCID: PMC10067031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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