Article
Profile of Pathogenic Mutations and Evaluation of Germline Genetic Testing Criteria in Consecutive Breast Cancer Patients Treated at a North Indian Tertiary Care Center.
Annals of surgical oncology - 1 Feb 2022
Mittal Abhenil, Deo S V S, Gogia Ajay, Batra Atul, Kumar Akash, Bhoriwal Sandeep, Deb Koushik Sinha, Dhamija Ekta, Thulkar Sanjay, Ramprasad V L, Olopade Olufunmilayo, Pramanik Raja
Abstract excerpt
BACKGROUND: The burden of hereditary breast cancer in India is not well defined. Moreover, genetic testing criteria (National Comprehensive Cancer Network [NCCN] and Mainstreaming Cancer Genetics [MCG] Plus) have never been validated in the Indian population. METHODS: All new female breast cancer patients from 1st March 2019 to 28th February 2020 were screened. Those providing informed consent and without...
Topics
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Female
- Genetic Predisposition to Disease
- Genetic Testing
- Germ Cells
- Germ-Line Mutation
- Humans
- Middle Aged