Evaluation of Germline Genetic Testing Criteria in a Hospital-Based Series of Women With Breast Cancer.

doi:10.1200/JCO.19.02190

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Article

Evaluation of Germline Genetic Testing Criteria in a Hospital-Based Series of Women With Breast Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 May 2020

Yadav Siddhartha, Hu Chunling, Hart Steven N, Boddicker Nicholas, Polley Eric C, Na Jie, Gnanaolivu Rohan, Lee Kun Y, Lindstrom Tricia, Armasu Sebastian, Fitz-Gibbon Patrick, Ghosh Karthik, Stan Daniela L, Pruthi Sandhya, Neal Lonzetta, Sandhu Nicole, Rhodes Deborah J, Klassen Christine, Peethambaram Prema P, Haddad Tufia C, Olson Janet E, Hoskin Tanya L, Goetz Matthew P, Domchek Susan M, Boughey Judy C, Ruddy Kathryn J, Couch Fergus J

Abstract excerpt

PURPOSE: To determine the sensitivity and specificity of genetic testing criteria for the detection of germline pathogenic variants in women with breast cancer. MATERIALS AND METHODS: Women with breast cancer enrolled in a breast cancer registry at a tertiary cancer center between 2000 and 2016 were evaluated for germline pathogenic variants in 9 breast cancer predisposition genes (ATM, BRCA1, BRCA2, CDH1, CHEK2,...

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Identifiers

PMID: 32125938
DOI: 10.1200/JCO.19.02190
PMCID: PMC7193748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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