Article
Genetic testing for hereditary predisposition to breast cancer in the real world: Initial experience.
Breast disease - 1 Jan 2022
da Silva Fontinele Danilo Rafael, Assunção Ribeiro da Costa Rafael Everton, da Silva Magalhães Maria Kamila, Vieira Sabas Carlos
Abstract excerpt
BACKGROUND: Around 5%-10% of breast cancers are due to hereditary breast and ovarian cancer syndrome. Genetic testing is important to identify these cases, enabling the adoption of specific risk-reducing treatment strategies. OBJECTIVE: To analyze the performance of genetic testing and its implications in patients with indication of genetic testing to identify hereditary predisposition to breast cancer. METHODS:...
Topics
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Cross-Sectional Studies
- Female
- Genetic Predisposition to Disease
- Genetic Testing
- Germ-Line Mutation
- Humans
- Ovarian Neoplasms