Article
Biomarker concordance between primary colorectal cancer and ovarian metastases: a Dutch cohort study.
Journal of cancer research and clinical oncology - 1 Aug 2023
van der Meer Richard, Jeuken Judith W M, Bosch Steven L, van Erning Felice N, Simkens Lieke H J, de Hingh Ignace H J T, Roumen Rudi M H
Abstract excerpt
PURPOSE: The genetic characteristics and mismatch repair (MMR) status of the primary tumor and corresponding metastases in colorectal cancer (CRC) are generally considered to be highly concordant. This implies that either the primary or metastatic tumor can be used for testing gene mutation and MMR status. However, whether this is also true for CRC and their ovarian metastases is currently unknown. Ovarian...
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