Article
Mismatch repair status between primary colorectal tumor and metastatic tumor, a retrospective consistent study.
Bioscience reports - 20 Dec 2019
Wang Zheng, Tang Xiaoli, Wu Xiaoqing, Yang Meiyuan, Wang Daorong
Abstract excerpt
Objectives Mismatch repair (MMR) and Microsatellite instability (MSI) are critical when considering immunotherapy and chemotherapeutic drugs an option for patients with colorectal cancer (CRC). We investigated the consistence of MMR status as well as MSI between primary CRC and metastatic tumor to see if the expression of four MMR proteins and the status of MSI are congruent in primary tumor and metastatic tumor....
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