Article

Single-cell Multi-omics reveal heterogeneity and metastasis potential in different liver cancer cell lines

2020-11-05

Abstract excerpt

Hepatocellular carcinoma (HCC) is a malignant neo-plasm with a high recurrence and metastatic rate, accounted for poor prognosis. Commonly existed heterogeneity is concerned with neoplasia, cancer progression, therapeutic resistance and metastasis is the principal cause of cancer lethality. As development of multi-omics methods in single-cell technology provides multi-faceted insight into disease processes in the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 50e8c78d-4d1e-503d-8d9b-c40cec9826ff
DOI: 10.1101/2020.11.03.367532

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-cell Multi-omics reveal heterogeneity and metastasis potential in different liver cancer cell linesDOI 10.1101/2020.11.03.367532Read

Understanding the heterogeneity in liver hepatocellular carcinoma with a special focus on malignant cell through single-cell analysisSemantic proximity Read

Single-cell tumor heterogeneity landscape of hepatocellular carcinoma: unraveling the pro-metastatic subtype and its interaction loop with fibroblastsSemantic proximity Read

Application of Single-Cell Multi-Omics in Dissecting Cancer Cell Plasticity and Tumor HeterogeneitySemantic proximity Read

Single‐Cell Transcriptome Analysis Uncovers Intratumoral Heterogeneity and Underlying Mechanisms for Drug Resistance in Hepatobiliary Tumor OrganoidsSemantic proximity Read

Single-cell and spatial architecture of primary liver cancerSemantic proximity Read

Application of single-cell and spatial omics in deciphering cellular hallmarks of cancer drug response and resistanceSemantic proximity Read

Single-cell analysis reveals the intra-tumor heterogeneity and identifies MLXIPL as a biomarker in the cellular trajectory of hepatocellular carcinomaSemantic proximity Read

Deciphering the heterogeneous niche in the tumor progression of hepatocellular carcinoma: a Spatial single-cell landscape and multi-omics atlas analysisSemantic proximity Read

The heterogeneity of cellular metabolism in the tumour microenvironment of hepatocellular carcinoma with portal vein tumour thrombusSemantic proximity Read

Cellular heterogeneity and plasticity in liver cancerSemantic proximity Read

Intratumoral heterogeneity of hepatocellular carcinoma: From single-cell to population-based studiesSemantic proximity Read

Genomic and the tumor microenvironment heterogeneity in multifocal hepatocellular carcinomaSemantic proximity Read