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Genomic heterogeneity in pancreatic cancer organoids and its stability with culture

19 Dec 2022

Abstract excerpt

The establishment of patient-derived pancreatic cancer organoid culture in recent years creates an exciting opportunity for researchers to perform a wide range of in vitro studies on a model that closely recapitulates the tumor. One of the outstanding question in pancreatic cancer biology is the causes and consequences of genomic heterogeneity observed in the disease. However, to use pancreatic cancer organoids...

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PMID: 36535941
DOI: 10.1038/s41525-022-00342-9

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