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Article

The molecular and cellular heterogeneity of pancreatic ductal adenocarcinoma.

Nature reviews. Gastroenterology & hepatology - 20 Dec 2011

Samuel Nardin, Hudson Thomas J

Abstract excerpt

Current standard therapies for pancreatic ductal adenocarcinoma have failed to attenuate the aggressiveness of this disease or confer notable improvements in survival. Previous molecular research into pancreatic cancers, along with advances in sequencing technologies, have identified many altered genes in patients with pancreatic cancer and revealed the marked genetic heterogeneity of individual tumors. Thus, the...

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PMID: 22183185
DOI: 10.1038/nrgastro.2011.215

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