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Article

Phenotypic, Genomic, and Transcriptomic Heterogeneity in a Pancreatic Cancer Cell Line.

Pancreas - 1 Oct 2024

Xie Gengqiang, Zhang Liting, Usman Olalekan H, Kumar Sampath, Modak Chaity, Patel Dhenu, Kavanaugh Megan, Mallory Xian, Wang Yue Julia, Irianto Jerome

Abstract excerpt

OBJECTIVE: To evaluate the suitability of the MIA PaCa-2 cell line for studying pancreatic cancer intratumor heterogeneity, we aim to further characterize the nature of MIA PaCa-2 cells' phenotypic, genomic, and transcriptomic heterogeneity. MATERIALS AND METHODS: MIA PaCa-2 single-cell clones were established through flow cytometry. For the phenotypic study, we quantified the cellular morphology, proliferation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38710020
DOI: 10.1097/MPA.0000000000002371
PMCID: PMC11384550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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