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Article

Structural and functional consequences of the H180A mutation of the light-driven sodium pump KR2.

Biophysical journal - 21 Mar 2023

Kriebel Clara Nassrin, Asido Marvin, Kaur Jagdeep, Orth Jennifer, Braun Philipp, Becker-Baldus Johanna, Wachtveitl Josef, Glaubitz Clemens

Abstract excerpt

Krokinobacter eikastus rhodopsin 2 (KR2) is a light-driven pentameric sodium pump. Its ability to translocate cations other than protons and to create an electrochemical potential makes it an attractive optogenetic tool. Tailoring its ion-pumping characteristics by mutations is therefore of great interest. In addition, understanding the functional and structural consequences of certain mutations helps to derive a...

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Identifiers

PMID: 36528791
DOI: 10.1016/j.bpj.2022.12.023
PMCID: PMC10111219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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