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Article

Sodium Ions Do Not Stabilize the Selectivity Filter of a Potassium Channel.

Journal of molecular biology - 23 Jul 2021

Hendriks Kitty, Öster Carl, Shi Chaowei, Sun Han, Lange Adam

Abstract excerpt

Ion conduction is an essential function for electrical activity in all organisms. The non-selective ion channel NaK was previously shown to adopt two stable conformations of the selectivity filter. Here, we present solid-state NMR measurements of NaK demonstrating a population shift between these conformations induced by changing the ions in the sample while the overall structure of NaK is not affected. We show...

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Identifiers

PMID: 34090923
DOI: 10.1016/j.jmb.2021.167091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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