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Article

Charting co-mutation patterns associated with actionable drivers in intrahepatic cholangiocarcinoma.

Journal of hepatology - 1 Mar 2023

Kendre Gajanan, Murugesan Karthikeyan, Brummer Tilman, Segatto Oreste, Saborowski Anna, Vogel Arndt

Abstract excerpt

BACKGROUND & AIMS: In recent years, intrahepatic cholangiocarcinoma (iCCA) has evolved as a "role model" for precision oncology in gastrointestinal cancers. However, its rarity, paired with its genomic heterogeneity, challenges the development and evolution of targeted therapies. Interrogating large datasets drives better understanding of the characteristics of molecular subgroups of rare cancers and enables the...

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Source

Identifiers

PMID: 36528236
DOI: 10.1016/j.jhep.2022.11.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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