Article
Identifying the Phenotypes of Tumor-Derived Extracellular Vesicles Using Size-Coded Affinity Microbeads.
Journal of the American Chemical Society - 28 Dec 2022
Wu Jiacheng, Lin Zhun, Zou Zhengyu, Liang Siping, Wu Minhao, Hu Tony Y, Zhang Yuanqing
Abstract excerpt
Tumor-derived extracellular vesicle (tEV) biomarkers can reflect cancer cell phenotypes and have great potential for cancer diagnosis and treatment. However, tEVs display high heterogeneity, and rapid and sensitive identification of EV biomarkers remains challenging due to their low expression. Spectral overlap also significantly limits the multiplex analysis of EV biomarkers by fluorescent probes. Herein, we...
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