Article
A Magnetically Driven Tandem Chip Enables Rapid Isolation and Multiplexed Profiling of Extracellular Vesicles.
Angewandte Chemie (International ed. in English) - 18 Dec 2023
Zhang Guihua, Wang Yaohui, Zhou Weihang, Lei Yanmei, Lu Jinsong, Yin Wenjin, Zhu Zhi, Yang Chaoyong, Zhang Peng
Abstract excerpt
The protein phenotypes of extracellular vesicles (EVs) have emerged as promising biomarkers for cancer diagnosis and treatment monitoring. However, the technical challenges in rapid isolation and multiplexed molecular detection of EVs have limited their clinical practice. Herein, we developed a magnetically driven tandem chip to achieve streamlined rapid isolation and multiplexed profiling of surface protein...
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