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An Aptamer-Engineered Phenotyping System for Extracellular Vesicles Based on Honeycomb-like Melamine-Formaldehyde Microspheres and Carbon Dot Nanozymes.

Analytical chemistry - 30 Jun 2026

Li Jing, Xu Liang, Fan Hao, Xie Xiao-Lin, Wu Cong-Ting, Liu Yi, Gong Wei, Li Lin, Xing Hui

Abstract excerpt

Molecular phenotyping of extracellular vesicles (EVs) holds promise for noninvasive cancer diagnosis; however, current methodologies encounter limitations in cost, throughput, and sensitivity. Herein, we developed an aptamer-engineered phenotyping system designed for multiplexed, cost-effective, and user-friendly detection of EV membrane proteins, utilizing a sensing array constructed from two tailored functional...

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PMID: 42296185
DOI: 10.1021/acs.analchem.6c01912

Genes

CD63
MUC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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