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Correlation between membrane proteins and sizes of extracellular vesicles and particles: A potential signature for cancer diagnosis

1 Dec 2023

Abstract excerpt

Extracellular vesicles and particles (EVPs) are recognized as ideal liquid biopsy tools for cancer detection, and membrane proteins are commonly used EVP biomarkers. However, bulk analysis of EVP membrane protein biomarkers typically fails to meet the clinical requirement for diagnostic accuracy. We investigated the correlation between the membrane protein expression level, the binding kinetics to aptamers and...

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PMID: 38050829
DOI: 10.1002/jev2.12391

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