Article

A simple immunoassay for extracellular vesicle liquid biopsy in microliters of non-processed plasma

2021-09-20

Abstract excerpt

Extracellular vesicles (EVs), released by most cell types, provide an excellent source of biomarkers in biological fluids. Here we describe a method that, using just a few microliters of patient’s plasma, identifies tumour markers exposed on EVs. Studying physico-chemical properties of EVs in solution, we demonstrate that they behave as stable colloidal suspensions and therefore, in immunocapture assays, many of t...

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Literature Corpus work: b396a87a-e9a7-5ce0-80ab-b5b1d96afbe0
DOI: 10.1101/2021.09.20.461033

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