Article
PLZF promotes the development of asthma tolerance via affecting memory phenotypes of immune cells.
International immunopharmacology - 1 Jan 2023
Li Na, Shi Tianyun, Zhang Meng, He Yanchao, Feng Jingjing, Mei Zhoufang, Su Xiao, Jie Zhijun
Abstract excerpt
Clarifying the pathogenesis of asthma and/or identifying the specific pathway underlying oral asthma tolerance (OT) would be of great significance. In our previous study, promyelocytic leukemia zinc finger (PLZF), which reportedly regulates memory phenotypes, was found to promote ovalbumin (OVA)-induced OT. Therefore, this study aimed to explore the regulatory effects of PLZF on memory phenotypes in asthma and OT...
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