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Article

Early RSV infection aggravates asthma-related Th2 responses by increasing the number of CD4+ TRM cells through upregulation of PLZF

26 Nov 2024

Abstract excerpt

Respiratory syncytial virus (RSV) infection is correlated with the chronic pathogenesis and exacerbation of asthma. However, the mechanism remains unclear. In this study, acute and memory (Mem) asthma models with early RSV infection are established to explore the persistence of the effects of RSV infection on asthma. Intravascular injection of an anti-CD45 antibody is performed to define CD4+ TRM cells...

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PMID: 39632661
DOI: 10.3724/abbs.2024220

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