Article
Changes in the phenotype and function of mucosal-associated invariant T cells in neutrophilic asthma.
International immunopharmacology - 1 May 2022
Wen Xue, Nian Siji, Wei Gang, Kang Pengyuan, Yang Yaqi, Li Lin, Ye Yingchun, Zhang Lulu, Wang Songping, Yuan Qing
Abstract excerpt
Asthma is a chronic heterogeneous inflammatory disease. Most neutrophilic asthma (NA) cases are severe asthma involving many inflammatory cells and mediators, although the specific pathogenesis is not clear. Mucosal-associated invariant T (MAIT) cells as innate-like T lymphocytes play an important role in the immune response in asthma by producing cytokines. In this study, we evaluated the phenotype and function...
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