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Article

A genetic correlation and bivariate genome-wide association study of grip strength and depression.

PloS one - 1 Jan 2022

Zhang Tianhao, Ji Lujun, Luo Jia, Wang Weijing, Tian Xiaocao, Duan Haiping, Xu Chunsheng, Zhang Dongfeng

Abstract excerpt

Grip strength is an important biomarker reflecting muscle strength, and depression is a psychiatric disorder all over the world. Several studies found a significant inverse association between grip strength and depression, and there is also evidence for common physiological mechanisms between them. We used twin data from Qingdao, China to calculate genetic correlations, and we performed a bivariate GWAS to...

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Identifiers

PMID: 36520780
DOI: 10.1371/journal.pone.0278392
PMCID: PMC9754196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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