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Article

Multivariate genome-wide association study of depression, cognition, and memory phenotypes and validation analysis identify 12 cross-ethnic variants.

Translational psychiatry - 30 Jul 2022

Sun Jing, Wang Weijing, Zhang Ronghui, Duan Haiping, Tian Xiaocao, Xu Chunsheng, Li Xue, Zhang Dongfeng

Abstract excerpt

To date, little is known about the pleiotropic genetic variants among depression, cognition, and memory. The current research aimed to identify the potential pleiotropic single nucleotide polymorphisms (SNPs), genes, and pathways of the three phenotypes by conducting a multivariate genome-wide association study and an additional pleiotropy analysis among Chinese individuals and further validate the top variants...

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Identifiers

PMID: 35907915
DOI: 10.1038/s41398-022-02074-x
PMCID: PMC9338946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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