Article
Enriched pathways for major depressive disorder identified from a genome-wide association study.
The international journal of neuropsychopharmacology - 1 Nov 2012
Kao Chung-Feng, Jia Peilin, Zhao Zhongming, Kuo Po-Hsiu
Abstract excerpt
Major depressive disorder (MDD) has caused a substantial burden of disease worldwide with moderate heritability. Despite efforts through conducting numerous association studies and now, genome-wide association (GWA) studies, the success of identifying susceptibility loci for MDD has been limited, which is partially attributed to the complex nature of depression pathogenesis. A pathway-based analytic strategy to...
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