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Article

A sex-specific genome-wide association study of depression phenotypes in UK Biobank.

Molecular psychiatry - 1 Jun 2023

Silveira Patrícia Pelufo, Pokhvisneva Irina, Howard David M, Meaney Michael J

Abstract excerpt

There are marked sex differences in the prevalence, phenotypic presentation and treatment response for major depression. While genome-wide association studies (GWAS) adjust for sex differences, to date, no studies seek to identify sex-specific markers and pathways. In this study, we performed a sex-stratified genome-wide association analysis for broad depression with the UK Biobank total participants...

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Identifiers

PMID: 36750733
DOI: 10.1038/s41380-023-01960-0
PMCID: PMC10611579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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