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Article

Core-based voxel-wise T2-FLAIR mismatch analysis for differentiation of IDH-mutant astrocytomas from oligodendrogliomas.

Neuroradiology - 1 Aug 2026

Erol Seyit, Baytok Ahmet, Arı Ayşe, Özer Halil, Cebeci Hakan

Abstract excerpt

OBJECTIVE: This study aims to develop a voxel-wise quantitative framework for the T2-FLAIR mismatch signal in routine MRI scans to differentiate IDH-mutant astrocytomas from oligodendrogliomas. METHODS: This retrospective study analyzed 43 patients with confirmed diffuse gliomas (25 astrocytomas and 18 oligodendrogliomas) using preoperative T2-weighted and FLAIR MRI. A voxel-wise log-ratio mismatch map was...

Read the complete abstract on PubMed

Topics

Humans
Oligodendroglioma
Brain Neoplasms
Female
Astrocytoma
Diagnosis, Differential
Retrospective Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Male

Magnetic Resonance Imaging

Middle Aged

Mutation

Isocitrate Dehydrogenase

Adult

Sensitivity and Specificity

Aged

Image Interpretation, Computer-Assisted

Source

Identifiers

PMID: 42384075
DOI: 10.1007/s00234-026-04099-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

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