Article
An Expanded T2-FLAIR Mismatch Phenotype in IDH-Mutant Astrocytomas.
Journal of magnetic resonance imaging : JMRI - 1 Oct 2026
Hua Tiantian, Zhang Xiaokang, Li Junjie, Jin Ying, Qiu Jun, Liu Yuwei, Cheng Dan, Duan Yunyun, Liu Xing, Zhuo Zhizheng, Lin Song, Liu Yaou
Abstract excerpt
BACKGROUND: The T2-FLAIR mismatch (T2FM) sign is a highly specific imaging biomarker for isocitrate dehydrogenase (IDH)-mutant astrocytomas; however, its strict definition limits clinical applicability. PURPOSE: To determine whether an expanded T2FM (eT2FM) phenotype could improve identification of IDH-mutant astrocytomas and capture prognostic and biological information. STUDY TYPE: Retrospective. POPULATION:...
Read the complete abstract on PubMedTopics
- Humans
- Isocitrate Dehydrogenase
- Astrocytoma
- Phenotype
- Male
- Mutation
