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Article

Genetics and epigenetics of CLL.

Leukemia & lymphoma - 1 Mar 2023

Paul Pamella, Stüssi Georg, Bruscaggin Alessio, Rossi Davide

Abstract excerpt

Chronic lymphocytic leukemia (CLL) has a heterogeneous biological behavior, which is highly influenced by its immunogenetic, epigenetic, and genomic properties. The remarkably variable clinical course of the disease has been associated with genetic features such as chromosomal abnormalities, the presence of either high or low numbers of somatic hypermutations (SHM) in the variable region of the immunoglobulin...

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Identifiers

PMID: 36503384
DOI: 10.1080/10428194.2022.2153359

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