Article
Chronic lymphocytic leukaemia genomics and the precision medicine era.
British journal of haematology - 1 Sept 2017
Ghamlouch Hussein, Nguyen-Khac Florence, Bernard Olivier A
Abstract excerpt
Massive genomic analyses have underscored the diversity of chronic lymphocytic leukaemia (CLL) between patients. Genetic heterogeneity of tumour clones within a patient may fuel tumour evolution. Several recurrently deregulated intra-cellular pathways are candidates for targeted therapies that are very promising and are dramatically changing clinical patients' perspectives. In this review we present an overview...
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