Article
Genetic and epigenetic basis of chronic lymphocytic leukemia.
Current opinion in hematology - 1 Jul 2013
Martín-Subero José I, López-Otín Carlos, Campo Elías
Abstract excerpt
PURPOSE OF REVIEW: Next-generation sequencing of whole genomes, exomes and DNA methylomes in chronic lymphocytic leukemia (CLL) has provided the first comprehensive view of somatic mutations and methylation changes in this disease. This review summarizes the recent findings in this field and their impact on our current understanding of this neoplasm. RECENT FINDINGS: Genomic studies have revealed a remarkable...
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