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Advances in epigenetic alterations of chronic lymphocytic leukemia: from pathogenesis to treatment

16 Mar 2024

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with alterations in genetic expression and epigenetic modifications. In recent years, the new insight into epigenetics in the pathogenesis of CLL has been developed considerably, including DNA methylation, histone modification, RNA methylation, non-coding RNAs as well as chromatin remodeling. Epigenetic modification regulates various processes such as...

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PMID: 38492089
DOI: 10.1007/s10238-023-01268-x

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