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Article

Sirtuins (SIRTs) As a Novel Target in Gastric Cancer

1 Dec 2022

Abstract excerpt

Gastric cancer is a major health burden worldwide. Among all neoplasms, gastric cancer is the fifth most common and the third most deadly type of cancer. It is known that sirtuins (SIRTs), are NAD+-dependent histone deacetylases regulating important metabolic pathways. High expression of SIRTs in the human body can regulate metabolic processes; they prevent inflammation but also resist cell death and aging...

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PMID: 36499440
DOI: 10.3390/ijms232315119

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