Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SIRT4 acts as a tumor suppressor in gastric cancer by inhibiting cell proliferation, migration, and invasion

1 Jul 2018

Abstract excerpt

BACKGROUND: Previous study has proven that SIRT4 is downregulated in gastric cancer (GC), but the role of SIRT4 has not been clearly understood. The aim of our work was to explore in detail the function and mechanism of SIRT4 in GC. METHODS: A total of 86 pairs of GC tumor tissues and adjacent normal tissues were collected, and quantitative real-time polymerase chain reaction and Western blotting analyses were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endoplasmic Reticulum Stress and Disease
Share to PARP inhibition in cancer therapy
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30022839
DOI: 10.2147/ott.s156143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SIRT4 acts as a tumor suppressor in gastric cancer by inhibiting cell proliferation, migration, and invasionPMID 30022839Read ↗

SIRT2 Promotes the Migration and Invasion of Gastric Cancer through RAS/ERK/JNK/MMP-9 Pathway by Increasing PEPCK1-Related MetabolismSemantic proximity Read ↗

SIRT1 suppresses the migration and invasion of gastric cancer by regulating ARHGAP5 expressionSemantic proximity Read ↗

Sirtuins (SIRTs) As a Novel Target in Gastric CancerSemantic proximity Read ↗

miR-543 promotes gastric cancer cell proliferation by targeting SIRT1Semantic proximity Read ↗

SIRT1 is a regulator of autophagy: Implications in gastric cancer progression and treatmentSemantic proximity Read ↗

The Prognostic Role of SIRT1-Autophagy Axis in Gastric CancerSemantic proximity Read ↗

Overexpression of SIRT4 inhibits the proliferation of gastric cancer cells through cell cycle arrestSemantic proximity Read ↗

SIRT7 levels are downregulated and are an independent prognostic factor in gallbladder cancerSemantic proximity Read ↗

SIRT1 promotes the proliferation and metastasis of human pancreatic cancer cellsSemantic proximity Read ↗

Advances in Expression Regulation, Molecular Targeting Mechanisms, and Therapeutic Applications of the Let-7 MicroRNA Family in Gastric CancerSemantic proximity Read ↗

SIRT1: a novel regulator in colorectal cancerSemantic proximity Read ↗

SIRT5 regulates autophagy and apoptosis in gastric cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.