Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The sirtuin family in health and disease

29 Dec 2022

Abstract excerpt

Sirtuins (SIRTs) are nicotine adenine dinucleotide(+)-dependent histone deacetylases regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in numerous biological processes. Currently, seven mammalian homologs of yeast Sir2 named SIRT1 to SIRT7 have been identified. Increasing evidence has suggested the vital roles of seven members of the SIRT family in health and disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Autophagy in Disease and Therapy
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36581622
DOI: 10.1038/s41392-022-01257-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The sirtuin family in health and diseasePMID 36581622Read ↗

Sirtuin functions and modulation: from chemistry to the clinicSemantic proximity Read ↗

Sirtuin Modulators in Cellular and Animal Models of Human DiseasesSemantic proximity Read ↗

Sirtuins in mammals: insights into their biological functionSemantic proximity Read ↗

Sirtuin family in autoimmune diseasesSemantic proximity Read ↗

Sirt6 Deacetylase: A Potential Key Regulator in the Prevention of Obesity, Diabetes and Neurodegenerative DiseaseSemantic proximity Read ↗

Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7Semantic proximity Read ↗

From Sirtuin Biology to Human Diseases: An UpdateSemantic proximity Read ↗

SIRT2 as a Therapeutic Target for Age-Related DisordersSemantic proximity Read ↗

Sirtuins and their Biological Relevance in Aging and Age-Related DiseasesSemantic proximity Read ↗

The Roles of SIRT1 in CancerSemantic proximity Read ↗

Bioinformatic analysis of SIRT7 sequence and structureSemantic proximity Read ↗

Role of sirtuins in epigenetic regulation and aging controlSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.