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Article

The role of SIRT2 in cancer: A novel therapeutic target

25 May 2020

Abstract excerpt

Sirtuin 2 (SIRT2) belongs to the sirtuins family. It exists in many tissues and organs of the human body and regulates a wide range of biological functions. Studies have found that the abnormal expression of SIRT2 was associated with a variety of malignant tumors. SIRT2 possesses an important role in tumorigenesis, with both tumor-promoting and tumor-suppressing function. However, the mechanisms in which SIRT2...

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PMID: 32449165
DOI: 10.1002/ijc.33118

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