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Article

Slow growing behavior in African trypanosomes during adipose tissue colonization

8 Dec 2022

Abstract excerpt

When Trypanosoma brucei parasites, the causative agent of sleeping sickness, colonize the adipose tissue, they rewire gene expression. Whether this adaptation affects population behavior and disease treatment remained unknown. By using a mathematical model, we estimate that the population of adipose tissue forms (ATFs) proliferates slower than blood parasites. Analysis of the ATFs proteome, measurement of protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36481558
DOI: 10.1038/s41467-022-34622-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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