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IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic Trypanosoma brucei infection

2022-09-23

Abstract excerpt

<h4>Summary</h4> In the skin, Trypanosoma brucei colonises the subcutaneous white adipose tissue (scWAT) and harbours a pool of parasites that are proposed to be competent for forward transmission. The interaction between parasites, adipose tissue, and the local immune system is likely to drive the adipose tissue wasting and weight loss observed in cattle and humans infected with T. brucei . However, mechanisti...

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Literature Corpus work
ef8da449-5b63-5381-ad54-197f12d32ffe
DOI
10.1101/2022.09.23.509158
Open publication

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IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic Trypanosoma brucei infectionDOI 10.1101/2022.09.23.509158
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