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Adaptive metabolic reprogramming of the brain tissue during late-stage <i>Trypanosome brucei</i> infection maintains host learning and memory

2026-05-21

Abstract excerpt

Human African Trypanosomiasis (HAT) is a two-stage infection caused by Trypanosoma brucei ssp. In stage I the trypanosomes are in blood, lymph and tissue interstitial space and the infection progresses to stage II when the parasites enter the central nervous system (CNS), resulting in behavioural aberrations that proceed to coma and death. Here, we use a bioluminescent murine model of HAT to examine parasite loca...

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Literature Corpus work
8e6f87fc-d2b5-5039-a3ec-63e3c73314c9
DOI
10.64898/2026.05.15.725345
Open publication

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Adaptive metabolic reprogramming of the brain tissue during late-stage <i>Trypanosome brucei</i> infection maintains host learning and memoryDOI 10.64898/2026.05.15.725345
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