Article
Pleiotropic architectures of porcine immune and growth trait pairs revealed by a self-product-based transcriptome method.
Animal genetics - 1 Apr 2023
Han Pingping, Wang Chao, Zhang Wei, Wu Yalan, Wang Daoyuan, Zhao Shuhong, Zhu Mengjin
Abstract excerpt
Pleiotropy is an important biological phenomenon with complicated genetic architectures for multiple traits. To date, pleiotropy has been mainly identified by multi-trait genome-wide association studies, but this method has its disadvantages, and new developments for pleiotropy detection methods are needed. Here we define a novel metric, self-product, to measure individual-level co-variation of two traits, and...
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