Article
Genetically regulated hepatic transcripts and pathways orchestrate haematological, biochemical and body composition traits.
Scientific reports - 21 Dec 2016
Ponsuksili Siriluck, Trakooljul Nares, Hadlich Frieder, Haack Fiete, Murani Eduard, Wimmers Klaus
Abstract excerpt
The liver is the central metabolic organ and exhibits fundamental functions in haematological traits. Hepatic expression, haematological, plasma biochemical, and body composition traits were assessed in a porcine model (n = 297) to establish tissue-specific genetic variations that influence the function of immune-metabolism-correlated expression networks. At FDR (false discovery rate) <1%, more than 3,600...
Topics
- Animals
- Body Composition
- Gene Expression Profiling
- Gene Expression Regulation
- Genetic Association Studies
- Genetic Variation
- Genotype
- Hematology
- Liver
- Phenotype
- Polymorphism, Single Nucleotide