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Article

Characterization of immune pleiotropy of ESR1 gene in pigs.

Immunogenetics - 1 Oct 2020

Wu Yalan, Zhang Wei, Zhang Lingni, Wang Daoyuan, Zhao Shuhong, Zhu Mengjin

Abstract excerpt

It is well known that the estrogen receptor alpha gene (ESR1) affects the reproductive traits of pigs; however, the immune role of ESR1 gene has not yet been resolved. Here, we characterized the pleiotropic aspects of ESR1 gene in immunity using the pig model. Tissue expression profile showed that the ESR1 gene had a broad ectopic expression in multiple reproductive and immune-related tissues/organs, which...

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Source

Identifiers

PMID: 33063129
DOI: 10.1007/s00251-020-01178-2

Genes

ESR1
CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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