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Article

Highly recurrent BRAF p.V595E mutation in canine papillary oral squamous cell carcinoma.

Veterinary and comparative oncology - 1 Mar 2023

Peralta Santiago, Webb Suzin M, Katt William P, Grenier Jennifer K, Duhamel Gerald E

Abstract excerpt

Oral squamous cell carcinoma (OSCC) is the most common oral epithelial malignancy in dogs. It exhibits locally aggressive biological behaviour with the potential to metastasize, and a reported 1-year survival rate of 0% when left untreated. Expression studies suggest that aberrant MAPK signalling plays a key role in canine OSCC tumorigenesis, which is consistent with BRAF and HRAS MAPK-activating mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 36451536
DOI: 10.1111/vco.12869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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