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Article

Effective detection of BRAFV595E mutation in canine urothelial and prostate carcinomas using immunohistochemistry.

Veterinary and comparative oncology - 1 Jun 2024

Aeschlimann Leonore, Kehl Alexandra, Guscetti Franco, Posthaus Caroline, Aupperle-Lellbach Heike, Rottenberg Sven, de Brot Simone

Abstract excerpt

Canine urothelial carcinoma (UC) and prostate carcinoma (PC) frequently exhibit the BRAFV595E mutation, akin to the BRAFV600E mutation common in various human cancers. Since the initial discovery of the BRAF mutation in canine cancers in 2015, PCR has been the standard method for its detection in both liquid and tissue biopsies. Considering the similarity between the canine BRAFV595E and human BRAFV600E...

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PMID: 38659202
DOI: 10.1111/vco.12978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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