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Article

Functional genetic variation in 3'UTR of PARP1 indicates a decreased risk and a better severity of ischemic stroke.

The International journal of neuroscience - 1 Jul 2024

Gu Lujun, Wang Qingguang, Xu Gangtao, Liu Dinghua

Abstract excerpt

Aim of the study: Polymorphisms of DNA repair enzyme gene may alter the ability of damage repair, ischemic stroke susceptibility and outcome. This study aimed to explore the association of polymorphisms in PARP1 and the effects of interactions between genes in Chinese.Materials and methods: A total of 500 patients and 500 healthy controls were enrolled for genotyping. Results: Clinical information analysis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 36448327
DOI: 10.1080/00207454.2022.2151907

Genes

PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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