Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glioma risk associates with polymorphisms of DNA repair genes, XRCC1 and PARP1.

British journal of neurosurgery - 1 Oct 2010

Yosunkaya Elif, Kucukyuruk Baris, Onaran Ilhan, Gurel Cigdem B, Uzan Mustafa, Kanigur-Sultuybek Gonul

Abstract excerpt

Cancer develops through interactions between polygenic and environmental factors, and changes in DNA repair pathway can increase susceptibility to tumours. XRCC1 and PARP1 are two proteins that act cooperatively in base excision repair (BER) of DNA. The polymorphisms of genes coding these proteins may effect their action in BER pathway. In this study, we aimed to investigate the associations between glioma risk...

Topics

Join the communities discussing this publication.

Brain Neoplasms
DNA-Binding Proteins
DNA Repair
Glioma
Poly (ADP-Ribose) Polymerase-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Poly(ADP-ribose) Polymerases

X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 20868244
DOI: 10.3109/02688697.2010.489655

Genes

PARP1
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glioma risk associates with polymorphisms of DNA repair genes, XRCC1 and PARP1.PMID 20868244Read ↗

Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to glioma.Semantic proximity Read ↗

Glioma risks associate with genetic polymorphisms of XRCC1 gene in Chinese population.Semantic proximity Read ↗

Association between DNA repair gene polymorphisms and risk of glioma: a systematic review and meta-analysis.Semantic proximity Read ↗

Polymorphisms in DNA Repair Gene and Susceptibility to Glioma: A Systematic Review and Meta-Analysis Based on 33 Studies with 15 SNPs in 9 Genes.Semantic proximity Read ↗

Associations between three XRCC1 polymorphisms and glioma risk: a meta-analysis.Semantic proximity Read ↗

Three polymorphisms of DNA repair gene XRCC1 and the risk of glioma: a case-control study in northwest China.Semantic proximity Read ↗

Association between XRCC1 polymorphisms and glioma risk among Chinese population.Semantic proximity Read ↗

Association between PARP-1 V762A polymorphism and cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

Association between the XRCC1 polymorphisms and glioma risk: a meta-analysis of case-control studies.Semantic proximity Read ↗

A Comprehensive Meta-analysis of Genetic Associations Between Key Polymorphic Loci in DNA Repair Genes and Glioma Risk.Semantic proximity Read ↗

PARP-1 Val762Ala polymorphism and risk of cancer: a meta-analysis based on 39 case-control studies.Semantic proximity Read ↗

Polymorphisms in DNA repair genes and risk of glioma and meningioma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.