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Article

Poly (Adenosine Diphosphate Ribose) Polymerase-1 Single Nucleotide Polymorphism in the 3'-Untranslated Region for Ischemic Stroke Risk Reduction.

Current neurovascular research - 1 Jan 2021

Gu Lujun, Xu Gangtao, Liu Dinghua

Abstract excerpt

OBJECTIVE: To determine the effect of PARP1 polymorphism on gene interactions. METHODS: A total of 500 patients and 500 healthy controls were enrolled. RESULTS: Analysis of clinical data showed that patients with stroke, diabetes, hypertension, and elevated serum triglyceride levels had higher levels of alcohol and smoking. The polymorphism of PARP1rs8679 was inversely associated with the risk of ischemic stroke....

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PMID: 34530710
DOI: 10.2174/1567202618666210916122553

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