Article
Association between PARP-1 V762A polymorphism and cancer susceptibility: a meta-analysis.
Genetic epidemiology - 1 Jan 2012
Yu Hongping, Ma Hongxia, Yin Ming, Wei Qingyi
Abstract excerpt
Poly(ADP-ribose) polymerase-1 (PARP-1 catalyzes poly(ADP-ribosyl)ation to various proteins involved in many cellular processes, including DNA damage detection and repair and cell proliferation and death. PARP-1 has been implicated in human carcinogenesis, but the association between the most-studied PARP-1 V762A polymorphism (rs1136410) and risk of various cancers was reported with inconclusive results. The aim...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
