Article
Neonatal lethality of mouse A/J-7SM consomic strain is caused by an insertion mutation in the Dchs1 gene.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2023
Miyasaka Yuki, Kobayashi Takeshi, Gotoh Naoya, Kuga Masako, Kobayashi Misato, Horio Fumihiko, Hashimoto Katsunori, Kawabe Tsutomu, Ohno Tamio
Abstract excerpt
Homosomic mice of the A/J-7SM consomic mouse strain that introduced the entire chromosome 7 (Chr 7) of SM/J into the A/J strain exhibited neonatal lethality. We tentatively maintained segregating inbred strains (A/J-7ASM and A/J-7DSM) in which the central portion of Chr 7 was heterozygous for the A/J and SM/J strains, and the centromeric and telomeric sides of Chr 7 were homozygous for the SM/J strain, instead of...
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