Article
Four out of eight genes in a mouse chromosome 7 congenic donor region are candidate obesity genes.
Physiological genomics - 22 Sept 2011
Sarahan Kari A, Fisler Janis S, Warden Craig H
Abstract excerpt
We previously identified a region of mouse chromosome 7 that influences body fat mass in F2 littermates of congenic × background intercrosses. Current analyses revealed that alleles in the donor region of the subcongenic B6.C-D7Mit318 (318) promoted a twofold increase in adiposity in homozygous lines of 318 compared with background C57BL/6ByJ (B6By) mice. Parent-of-origin effects were discounted through...
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